Zesco United won the bragging rights after a 6-0 thrashing of Buildcon in the Ndola derby.
In Kitwe, Nkana scored a late goal to beat Nkwazi 2-1 while Green Eagles picked up a 2-1 away in Chambishi.
An own goal from Shadreck Banda earned Kabwe Warriors a 1-0 win over Kansanshi Dynamos.
Elsewhere, Forest Rangers and Red Arrows played out to a 1-1 draw.
Below are the results.
Zambian Super League Week 28 Results
Prison Leopards 0-0 Muza
Chambishi 1-2 Green Eagles (Eddie Sinyangwe (P) 90’ | Amity Shamende 45’, Gift Mwansa 72’)
Forest Rangers 1-1 Red Arrows (Lazarous Chishimba 54’ | Saddam Yusuf Phiri (P) 8’)
Kabwe Warriors 1-0 Kansanshi Dynamos (Shadreck Banda (OG) 73’)
Nkana 2-1 Nkwazi (Emmanuel Mutale 76’, Lameck Kafwaya 90’ | Carlos Kaoma 36’)
Nchanga Rangers 1-1 Lumwana Radiants (Elliot Kampukesa | Joe Simbuwa 36’)
Buildcon 0-6 Zesco United (Collins Sikombe 32’, 88’, Enock Sakala 54’, Lazarous Kambole 56’, Vincent Oburu 82’, Songa Chipyoka 89’)